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Johanna Roether

M.Sc. Johanna Roether


Applied Mechanics (AME)

Room: 206
Phone: +49 721 608 -48824
Fax: +49 721 608 -43758
johanna roetherZav6∂partner kit edu

 KIT - Campus Süd
Institut für Mechanische Verfahrenstechnik und Mechanik
Arbeitsgruppe Angewandte Mechanik

Gotthard-Franz-Straße 3, Geb. 50.31
76131 Karlsruhe

Microrheology of hyaluronic acid-based 3D scaffold materials for tissue engineering

Microrheology of hyaluronic acid-based 3D scaffold materials for tissue engineering

Tissue engineering requires biocompatible scaffold materials whose open-porous, three-dimensional architecture enables an adequate supply of nutrients to the cells. The mechanical properties of the matrices play a fundamental role not only in differentiation but also in the regulation of cell division and cell metabolism, because differentiated tissue cells such as keratinocytes and fibroblasts can also perceive the hardness and elasticity of their direct environment (mechanosensing) and adapt their metabolism to these conditions. Since in a macroporous, liquid-filled system the local rheological properties do not necessarily correspond to the macroscopically accessible parameters, the Multiple Particle Tracking method is used to determine microrheological properties of the network structure as well as the pore fluid. Thus, the direct environmental conditions in the network and in the pores can be evaluated locally in hyaluronic acid collagen cryogels.


Conference Contributions

D. Grijalva, J. Roether, Claude Oelschlaeger, Karlsruhe/DE

Microrheology Method for in-situ Characterization of Matrix Remodelling

Dimensional Control of Polymer Materials – From Synthesis to Function Biennial Meeting of the GDCh-Division of Macromolecular Chemistry together with SFB 1176

24-27 September 2018, Karlsruhe, DE


Johanna Roether, Sarah Bertels, Claude Oelschlaeger, Martin Bastmeyer, Norbert Willenbacher

Monitoring of matrix remodeling during living cell culture by microrheological measurements

5th TERMIS World Congress 2018, 4 – 8 September 2018, Kyoto, JAPAN


Johanna Roether, Claude Oelschlaeger, Norbert Willenbacher

Monitoring of Matrix Remodeling during Living Cell Culture by Microrheological Measurements

4th International Conference on Biomedical Polymers & Polymeric Biomaterials, 15-18 July 2018, Kraków, POLAND


J. Roether, C. Oelschlaeger, N. Willenbacher

Live Monitoring of Local Viscoelastic Properties of Collagen Cryogel Scaffolds during Matrix Remodeling in Cell Culture

Bone Tec – International Bone-Tissue-Engineering Conference, 12-14. October 2017, Munich, Germany


J. Roether, A. Rył, Technical University of Łódź, Poland, C. Oelschlaeger, N. Willenbacher

Mechanical Properties and Suitability for Cell Culture of Hyaluronic Acid, Chitosan and Collagen Based Scaffolds Obtained from Cryogelation

1st International Conference on Advances in Bio-Materials and Their Applications, 31 August -1 September 2017, London, UNITED KINGDOM


Johanna Roether, Claude Oelschlaeger, Norbert Willenbacher

Textural, macromechanical and microrheological properties of HA/collagen scaffolds and their influence on cell culture

European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society 2017, 26 - 30 June 2017, Davos, SWITZERLAND


J Roether, C Oelschlaeger, N Willenbacher

Synthesis, structural and micromechanical properties of 3D hyaluronic acid/collagen based cryogel scaffolds for tissue engineering

European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society 2016, 28 June – 1 July 2016, Uppsala, SWEDEN

Titel Autor Quelle

Johanna Roether, Kang-Yu Chu, Norbert Willenbacher, Amy Q. Shen, Nikhil Bhalla

Biosensors and Bioelectronics 142 (2019) 111528

Roether, Johanna; Bertels, Sarah; Oelschlaeger, Claude; Bastmeyer, Martin; Willenbacher, Norbert

PlosOne (2018)

Titel Typ Betreuer Datum